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ibicuruzwa

1-Fenil-3,4-dihydroisoquinoline (CAS # 52250-50-7)

Umutungo wa Shimi:

Inzira ya molekulari C15H13N
Misa 207.27
Ubucucike 1.07 ± 0.1 g / cm3 (Biteganijwe)
Ingingo yo gushonga 174 ° C.
Ingingo ya Boling 146.0-149.5 ° C (Kanda: 1.2 Torr)
Flash point 143.4 ° C.
Gukemura Chloroform (Buhoro), DMSO (Buhoro)
Umwuka 0.000408mmHg kuri 25 ° C.
pKa 5.29 ± 0.20 (Byahanuwe)
Imiterere y'Ububiko Ikidodo cyumye, Ubushyuhe bwicyumba
Ironderero 1.611

Ibicuruzwa birambuye

Ibicuruzwa

1-Fenil-3,4-dihydroisoquinoline (CAS # 52250-50-7)

1-Phenyl-3,4-dihydroisoquinoline, CAS nimero 52250-50-7, yerekanye igikundiro kidasanzwe mubijyanye na chimie nubuvuzi.

Uhereye ku miterere yimiti, molekile yayo ihujwe nubuhanga hamwe nuburyo bwimiterere nkitsinda rya fenyl hamwe nimpeta ya dihydroisoquinoline, kandi ubu buryo bwihariye bwo guhuza atome bwubaka igicu kidasanzwe cya elegitoroniki, gikora ibikorwa byihariye bya chimique no gutuza. Mubigaragara, mubisanzwe bigaragazwa nkibikomeye hamwe nuburyo runaka bwa kristu, ibara ryera cyane ryera cyangwa ritari ryera, kandi imiterere ya kirisiti isanzwe kandi itondekanye, ifasha kwezwa no gutunganywa hakoreshejwe uburyo bwo kongera gukora. Kubijyanye no gukemuka, byerekana uburyo bumwe bwo gusesa mumashanyarazi asanzwe nka Ethanol na acetone, ariko gukomera mumazi ni bike, bifitanye isano rya bugufi na polarite ya molekile, kandi binatanga umusingi wo guhitamo sisitemu yo gukemura nyuma yo gutandukana hamwe na synthesis reaction.
Kubijyanye na farumasi R&D ibyiringiro, ifite ibikorwa byibinyabuzima. Imiterere yimiti yibicuruzwa bisa nibya bimwe mubicuruzwa bisanzwe bikoresha imiti, byerekana ko bishobora kuba bifite intego zisa. Ubushakashatsi bwibanze bwerekana ko bushobora kugira ingaruka ku nzira zerekana ibimenyetso by’imitsi, kandi bikaba byitezwe ko bizagira uruhare mu iterambere ry’imiti mishya y’indwara zifata ubwonko, nk'indwara ya Alzheimer n'indwara ya Parkinson, mu kugenzura ubwandu bwa neurotransmitter budasanzwe no kubuza hyperapoptose ya selile. Muri icyo gihe, mu rwego rwo kurwanya ibibyimba, amatsinda akora mu miterere yayo ashobora kubangamira ikwirakwizwa, kwimuka no gutera ingirangingo z’ibibyimba, gufungura ibitekerezo bishya byo kuvura kanseri, byanze bikunze, ibyo biracyari kare. icyiciro cyubushakashatsi bwa laboratoire, kandi haracyari byinshi byubushakashatsi bugomba gukorwa mbere yubuvuzi.
Urebye kuri synthesis yinganda, uburyo bwa kijyambere bwa chimique synthèse yuburyo bushingiye cyane cyane, guhera kubikoresho byoroheje, binyuze muburyo butandukanye bwo kubaka skeletike igoye, inzira ikubiyemo kuzunguruka, gusimbuza, guhuza hamwe nubundi bwoko bwa reaction ya organic reaction; , abashakashatsi bakomeje kunoza imiterere yimyitwarire, kuzamura umusaruro, kugabanya ibiciro, kugirango bakemure ubushakashatsi bwimbitse kandi bushoboka n’umusaruro munini. Hamwe noguhuza kwikoranabuhanga muburyo butandukanye, iterambere ryuzuye rya 1-Phenyl-3,4-dihydroisoquinoline biteganijwe ko ryihuta, ritera imbaraga nshya mubuzima bwabantu niterambere ryubumenyi nikoranabuhanga.


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