1H-Pyrazole-3-carboxylicacid 5-methyl- （CAS # 696-22-0)
| Ibimenyetso bya Hazard | Xi - Kurakara |
| Kode y'ingaruka | R36 / 37/38 - Kurakaza amaso, sisitemu y'ubuhumekero n'uruhu. |
| Ibisobanuro byumutekano | S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S37 / 39 - Kwambara uturindantoki dukwiye no kurinda amaso / kurinda amaso |
Intangiriro
Nibintu kama hamwe na formula ya chimique C5H5N2O2. Mubisanzwe ni ibara ritagira ibara ryumuhondo ryijimye.
Urusobekerane rufite amatsinda abiri akora, rimwe ni impeta ya pyrazole naho irindi ni itsinda rya acide karubike. Ifite imbaraga ziciriritse kandi irashobora gushonga mumazi hamwe nibisanzwe bisanzwe. Itsinda rya methyl muburyo bwaryo rituma hydrophobique.
Nka compound ya heterocyclic, 5-methyl-ifite ibikorwa bitandukanye byibinyabuzima. Ikoreshwa cyane mubushakashatsi bwa farumasi no guhuza imiti, akenshi nkibikoresho fatizo cyangwa hagati. Porogaramu zihariye zirimo synthesis ya vitamine B1 igereranya, udukoko twica udukoko, insimburangingo ya plavix (uruganda rukoreshwa mu kubuza imikurire y’ibihingwa), nibindi nkibyo.
Gutegura, 5-methyl-irashobora kuboneka mugukora azote ya azote yimpeta ya pyrazole hamwe na methylating agent (urugero: methyl iodide). Ubu buryo bukorwa na N-methylation reaction, uburyo busanzwe ni reaction ya nucleophile ijyanye na reagent ya N-methyl.
