1H-Pyrrolo [2 3-b] pyridine 6-mikorerexy- （CAS # 896722-53-5)

Intangiriro

6-mikorerexy-1H-cryrolo [2,3-b] pyridine ni ifumbire mvaruganda hamwe na formula ya chimique C9H8N2O. Imiterere yacyo niyi ikurikira:

1. Kugaragara: 6-mikorerexy-1H-chrrolo [2,3-b] pyridine nta ibara rifite kuri kirisiti y'umuhondo.

2. Gushonga ingingo: hafi 105-108 ℃.

3. Ingingo itetse: hafi 325 ℃.

4.

6-mikorerexy-1H-yrrolo [2,3-b] pyridine ifite akamaro gakomeye mubushakashatsi bwa farumasi nubumara, nkibi:

1. Kuvura ibiyobyabwenge: Ikoreshwa cyane mubushakashatsi no guteza imbere anti-tumor, anti-inflammatory, anti-kanseri nindi miti.

2.

Uburyo bwo gutegura 6-mikorerexy-1H-cryrolo [2,3-b] pyridine nuburyo bukurikira:

1. N-methylation reaction ya indole: Indole ikorwa na methyl halide kugirango itange indole 6-methyl, hanyuma ikore hamwe na N-methyl vinyl amine kugirango itange 6-mikorerexy-1H-cryrolo [2,3-b] pyridine.

2. Redox reaction ya indole: 6-mikorerexy-1H-pyridolo [2,3-b] pyridine irashobora kuboneka mugukora indole hamwe na nitrite ya sodium na tert-butyl peroxide.

Ku bijyanye n’amakuru y’umutekano, hari ubushakashatsi buke ku burozi n’akaga ka 6-mikorerexy-1H-pyridolo [2,3-b] pyridine, bityo isuzuma ryihariye ry’umutekano rikeneye ubundi bushakashatsi. Mugihe ukora ubushakashatsi cyangwa gusaba, gukosora ibikorwa byubushakashatsi hamwe ningamba zumutekano bigomba gukurikizwa, ukirinda guhura nuruhu n'amaso, witondere ingamba zo kubarinda, kandi wirinde guhumeka aerosole cyangwa ivumbi. Nibiba ngombwa, bigomba gukoreshwa ahantu hafite umwuka mwiza.