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2 4-Dichloro-5-methylpyrimidine （CAS # 1780-31-0) Ishusho Yerekanwe
  • 2 4-Dichloro-5-methylpyrimidine （CAS # 1780-31-0) 1

2 4-Dichloro-5-methylpyrimidine （CAS # 1780-31-0)

Umutungo wa Shimi:

Inzira ya molekulari C5H4Cl2N2
Misa 163
Ubucucike 1,39 g / mL kuri 25 ° C (lit.)
Ingingo yo gushonga 26-28 ° C (lit.)
Ingingo ya Boling 108-109 ° C / 11 mmHg (lit.)
Flash point > 230 ° F.
Gukemura Gukemura muri chloroform, ether, Ethyl acetate na toluene
Umwuka 0.079mmHg kuri 25 ° C.
Kugaragara ifu kumeneka kugirango isukure amazi
Ibara Umweru cyangwa Ibara Kuri Hafi Yera Cyangwa Hafi Ibara
pKa -2.44 ± 0.29 (Byahanuwe)
Imiterere y'Ububiko Ikirere cyinjiza, 2-8 ° C.

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Ibyago n'umutekano

Ibimenyetso bya Hazard C - Kubora
Kode y'ingaruka 34 - Bitera gutwika
Ibisobanuro byumutekano S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi.
S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso.
S45 - Mugihe habaye impanuka cyangwa niba wumva utameze neza, shaka inama zubuvuzi ako kanya (erekana ikirango igihe cyose bishoboka.)
S27 - Kuramo ako kanya imyenda yose yanduye.
Indangamuntu ya Loni UN 3261 8 / PG 2
WGK Ubudage 3
TSCA Yego
Kode ya HS 29335990
Icyiciro cya Hazard 8
Itsinda ryo gupakira III

2 4-Dichloro-5-methylpyrimidine （CAS # 1780-31-0) Amakuru

Koresha 2, 4-dichloro-5-methylpyrimidine irashobora gukoreshwa mugutegura 2-fluoro-5-trifluoromethylpyrimidine. 2-fluoro-5-trifluoromethylpyrimidine nintera yingenzi muguhuza imiti yimiti, ishobora gukoreshwa muguhuza impeta ya dihydrofuran yimvange, hamwe nimpeta ya dihydrofuran yahujwe ishobora gukoreshwa nka G protein ihujwe na reseptor GPR119, kugirango ivure diyabete, umubyibuho ukabije n'indwara ya dyslipidemiya. Byongeye kandi, 2-fluoro-5-trifluoromethylpyrimidine irashobora kandi gukoreshwa nkigihe gito muguhuza imiti yo kuvura indwara ya Alzheimer na schizofrenia.
kwitegura Methyluracil 5g 1.19mol), reaction yo kubungabunga ubushyuhe 2H. Nyuma yo kurangiza kwifata, fosifore oxychloride yagaruwe no kuyungurura munsi yumuvuduko ukabije, kandi gusibanganya umuvuduko wagabanutse byakomeje kubona 88g (0.54mol) ya 2, 4-dichloro-5-methylpyrimidine ku musaruro wa 91.5%.
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