2-Amino-3-bromo-5- (trifluoromethyl) -pyridine （CAS # 79456-30-7)
| Icyiciro cya Hazard | IRRITANT |
Intangiriro
2-Amino-3-brom-5- (trifluoromethyl) pyridine ni ifumbire mvaruganda hamwe na formula ya chimique C6H4BrF3N2. Imiterere ya molekile yayo irimo impeta ya pyridine na atom ya bromine, hamwe nitsinda rya amino hamwe nitsinda rya trifluoromethyl.
Imiterere yumubiri niyi ikurikira:
Kugaragara: Umweru ukomeye
Ingingo yo gushonga: 82-84 ° C.
Ingingo yo guteka: 238-240 ° C.
Ubucucike: 1.86g / cm³
Gukemura: Gushonga buhoro mumazi, gushonga mumashanyarazi nka Ethanol, ether na dichloromethane.
Bumwe mu buryo bukoreshwa bwa 2-Amino-3-bromo-5- (trifluoromethyl) pyridine ni nka farumasi hagati. Irashobora gukoreshwa mugutegura ibinyabuzima bikora, nkibiyobyabwenge, imiti yica udukoko n amarangi. Byongeye kandi, irashobora kandi gukoreshwa nka ligand kugirango igire uruhare mubikorwa byimiti iterwa na ioni yicyuma, nkibikoresho bya catalizike reaction hamwe no kumva imiti.
Uburyo bwa synthesis yuburyo bushobora kugerwaho na bromopyridine na reaction ya amination. Intambwe zihariye zirimo gukora bromopyridine hamwe na ammonia, gusimbuza atom ya bromine hamwe nitsinda rya amino mubihe byibanze, hanyuma ugashyiraho itsinda rya trifluoromethyl munsi ya trifluoromethylation reagent.
Kubyerekeranye namakuru yumutekano, 2-Amino-3-bromo-5- (trifluoromethyl) pyridine ni uruganda kama kandi rugomba gukoreshwa hitawe kubikorwa byo gukingira. Irashobora kugira ingaruka mbi kandi yangirika kumaso, uruhu hamwe na sisitemu yubuhumekero. Irinde guhura bitaziguye mugihe gikora kandi urebe neza ko umwuka uhumeka neza. Birasabwa kwambara ibikoresho byokwirinda nkikirahure kirinda, gants na masike yo gukingira mugihe ukoresheje. Mugihe cyo kujugunya, nyamuneka ukurikize ibisabwa byo guta imyanda yaho. Mugihe cyo kubika, igomba kubikwa mubushyuhe buke, ahantu humye kandi ihumeka, birinda guhura na okiside na aside.
