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2-Amino-6-bromopyridine （CAS # 19798-81-3) Ishusho Yerekanwe
  • 2-Amino-6-bromopyridine （CAS # 19798-81-3) 1

2-Amino-6-bromopyridine （CAS # 19798-81-3)

Umutungo wa Shimi:

Inzira ya molekulari C5H5BrN2
Misa 173.01
Ubucucike 1.710 ± 0.06 g / cm3 (Biteganijwe)
Ingingo yo gushonga 88-91 ° C (lit.)
Ingingo ya Boling 273.0 ± 20.0 ° C (Biteganijwe)
Flash point 118.9 ° C.
Amazi meza Gushonga buhoro mumazi.
Gukemura Chloroform (Buhoro), Methanol (Byoroheje)
Umwuka 0.0059mmHg kuri 25 ° C.
Kugaragara Ifu yera yijimye
Ibara Umuhondo gahoro gahoro
pKa 2.73 ± 0.24 (Byahanuwe)
Imiterere y'Ububiko Komeza ahantu hijimye, Gufunzwe byumye, Ubushyuhe bwicyumba

Ibicuruzwa birambuye

Ibicuruzwa

Ibyago n'umutekano

Kode y'ingaruka R36 / 37/38 - Kurakaza amaso, sisitemu y'ubuhumekero n'uruhu.
R20 / 21/22 - Byangiza muguhumeka, guhura nuruhu kandi niba byamizwe.
Ibisobanuro byumutekano S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi.
S36 - Kwambara imyenda ikingira.
S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso.
WGK Ubudage 3
Kode ya HS 29333999
Icyiciro cya Hazard IRRITANT

 

 

2-Amino-6-bromopyridine （CAS # 19798-81-3) Amakuru

Incamake 2-amino yasimbuwe na azote irimo ibice bitandatu bigize heterocyclic igizwe ningirakamaro mu nganda z’imiti, nka 2-amino -6-Bromopyridine ni imwe mu nzego zingenzi mu miti y’ubukorikori na molekile y’ubuhinzi, kandi ikoreshwa cyane muri synthesis y'ibicuruzwa bisanzwe, ibiyobyabwenge, ibikoresho bya luminescent hamwe nimiti itandukanye myiza.
Gusaba 2-amino yasimbuwe na azote irimo ibice bitandatu bya heterocyclic yibintu bifite akamaro gakomeye mu nganda z’imiti, nka 2-amino -6-Bromopyridine ni imwe mu nzego z’ingenzi mu miti y’ubukorikori na molekile y’imiti y’ubuhinzi, kandi ikoreshwa cyane muri synthesis y'ibicuruzwa bisanzwe, ibiyobyabwenge, ibikoresho bya luminescent hamwe nimiti itandukanye myiza.
Kwitegura Gutegura 2-amino-6-bromopyridine: Ongeramo 2-fluoro-6-bromo-pyridine (1mmol), pentamidine hydrochloride (2mmol), sodium tert-butoxide (3mmol), HO (0.5mL) na diethylene glycol dimethyl ether (2.5 mL) mumashanyarazi ya ml 25. Igisubizo cyakozwe kuri 150 ℃ mumasaha 24. Igisubizo kirangiye, cyakonje kugeza ubushyuhe bwicyumba. Ongeramo 10mL ya Ethyl acetate kugirango uzimye reaction, ongeramo 6mL yamazi yumunyu wuzuye kugirango ukarabe, utandukane icyiciro kama, hanyuma ukuremo icyiciro cyamazi hamwe na Ethyl acetate inshuro 3 (dosiye ya Ethyl acetate buri gihe ni 6mL) hanyuma uhuze organic icyiciro, ongeramo anhydrous sodium sulfate kugirango yumuke, ukureho ibishishwa birimo ibishishwa kama na organic organique ukoresheje vacuum distillation, hanyuma utandukane ibinyabuzima byifashishwa na chromatografiya kubona ibicuruzwa bigenewe 2-amino-6-bromopyridine n'umusaruro wa 93%.
Koresha abahuza imiti.
kuri synthesis nziza ya 7-azafindole mumasafuriya; kuri synthesis yimiti irwanya virusi itera sida

 

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