2-Bromo-5- (trifluoromethyl) pyridine （CAS # 50488-42-1)

Umutungo wa Shimi:

Inzira ya molekulari	C6H3BrF3N
Misa	225.99
Ubucucike	1.707 ± 0.06 g / cm3 (Biteganijwe)
Ingingo yo gushonga	44-48 ° C.
Ingingo ya Boling	78 ° C.
Flash point	78-81 ° C / 30mm
Gukemura	Gukemura muri methanol na Ethanol.
Umwuka	0mmHg kuri 25 ° C.
Kugaragara	Urushinge rwumuhondo
pKa	-1? + -. 0.10 (Byahanuwe)
Imiterere y'Ububiko	Komeza ahantu hijimye, Gufunzwe byumye, Ubushyuhe bwicyumba
Ironderero	1.572
MDL	MFCD00153086
Ibintu bifatika na shimi	Hanze ya kirisiti
Koresha	Substrate ya palladium-catisale α-arylation ya refomatsky reagents

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Ibicuruzwa birambuye

Ibicuruzwa

Kode y'ingaruka	R25 - Uburozi iyo bumize R36 / 37/38 - Kurakaza amaso, sisitemu y'ubuhumekero n'uruhu. R20 / 21/22 - Byangiza muguhumeka, guhura nuruhu kandi niba byamizwe.
Ibisobanuro byumutekano	S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso. S22 - Ntugahumeke umukungugu. S36 - Kwambara imyenda ikingira.
Indangamuntu ya Loni	UN 2811 6.1 / PG 3
WGK Ubudage	3
Kode ya HS	29333990
Icyiciro cya Hazard	IRRITANT
Itsinda ryo gupakira	Ⅲ

Intangiriro

2-Bromo-5- (trifluoromethyl) pyridine (izwi kandi nka BTFP) ni ifumbire mvaruganda. Ibikurikira nintangiriro yimiterere yabyo, imikoreshereze, uburyo bwo gutegura namakuru yumutekano:

Ubwiza:

- Kugaragara: Umweru ukomeye

- Uburemere bwa molekuline: 206.00 g / mol

- Gukemura: BTFP irashobora gushonga byoroshye mumashanyarazi (urugero, alcool, ethers, ketone) ariko ntibishonga mumazi.

Koresha:

- Nka synthesis intermediaire: BTFP ikoreshwa cyane mugutegura intungamubiri za organic synthesis, nkibintu bya pyridine, ibimera bya aromatic, nibindi.

- Nka ligande: BTFP irashobora gukoreshwa nka ligand kumashanyarazi kandi igira uruhare mubikorwa bitandukanye bya catalitiki no gutegura ibikoresho bikora.

- Nka reagent: BTFP igira uruhare runini muri synthesis organique, nko guhuza reaction, reaction yo gusimbuza, no kugabanya reaction.

Uburyo:

2-Bromo-5- (trifluoromethyl) pyridine irashobora guhuzwa nintambwe zikurikira:

1. Kuramo pyridine 2-amino-5- (trifluoromethyl) pyridine mumashanyarazi akwiye, nka alcool cyangwa ketone.

2. Ongeramo ibice bya bromine (urugero: hydrogen bromide, methyl bromide).

3. Kora reaction ku bushyuhe bukwiye no gukurura ibintu.

4. Shungura ibicuruzwa hanyuma ukore kristu no kweza.

Amakuru yumutekano:

- BTFP irashobora gukomera cyangwa korohereza ubushyuhe buke, nyamuneka ubike ubushyuhe bwicyumba kandi wirinde korohereza.

- Kwambara uturindantoki dukingira hamwe nikirahure mugihe cyo gukora kugirango wirinde guhura nuruhu n'amaso.

- Irinde guhumeka umukungugu cyangwa imyuka, kuko BTFP ishobora kugira ingaruka mbi mumyanya y'ubuhumekero.

- Reba mu gitabo cy’umutekano kijyanye no gukoresha cyangwa gukoresha BTFP, no kujugunya imyanda n’umuti bikwiye.