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2- (DIPHENYLMETHYL) -QUINUCLIDIN-3-UMWE (CAS # 32531-66-1)

Umutungo wa Shimi:

Inzira ya molekulari C20H21NO
Misa 291.39
Ubucucike 1.17 ± 0.1 g / cm3 (Biteganijwe)
Ingingo ya Boling 432.8 ± 28.0 ° C (Biteganijwe)
pKa 6.19 ± 0.40 (Byahanuwe)
Koresha 2-diphenylmethylquinuclidin-3-imwe nkibikomoka kuri ketone, irashobora gukoreshwa nkumuhuza wimiti.

Ibicuruzwa birambuye

Ibicuruzwa

2-. (DIPHENYLMETHYL)

Uhereye ku isesengura ryimiterere yimiti, imyubakire idasanzwe ya molekile ihuza ibice byubatswe bya methenyl methyl na quinine. Itsinda rya Diphenyl methyl rizana sisitemu nini yo guhagarika no guhuza ibintu, bigira ingaruka ku bicu bya elegitoronike ya molekile, mugihe igice cya cinine cyclic ketone giha molekile ibintu bimwe na bimwe bikomeye kandi byibanze, kandi byombi byubaka byubaka imiterere ihamye ariko ikora. Mubisanzwe muburyo bwifu ya kirisiti yera, ubu buryo bukomeye bworohereza kubika, gutwara, no gutunganya nyuma. Kubijyanye no gukemuka, ifite imbaraga zo gukemuka neza mumashanyarazi adafite polar nka benzene na toluene, ibyo bikaba biterwa nakarere katari polarike ya molekile, mugihe gafite imbaraga nke mumashanyarazi menshi nkamazi na alcool, aribyo ni ingenzi cyane kubijyanye no guhitamo ibisubizo, gutandukana no kweza intambwe muri synthesis.
Kubijyanye nubushobozi bwo kuvura, imiterere yacyo isa niy'imiti imwe n'imwe ihari yo mu mutwe, byerekana ko ishobora gukora ku ntego zijyanye na sisitemu yo hagati. Ubushakashatsi bwakozwe mbere bwerekanye ko bushobora kugira ingaruka ku gufata no kurekura imiyoboro ya neurotransmitter, kandi bikaba biteganijwe ko izakoreshwa mu kuvura indwara zo mu mutwe nka sikizofreniya no kwiheba, kandi bikazamura ibimenyetso by’abarwayi mu kwivanga mu bimenyetso bidasanzwe by’imitsi idasanzwe. Ariko, kuri ubu, inyinshi muri zo ziri mu cyiciro cy’ubushakashatsi bw’akagari n’ubushakashatsi bw’icyitegererezo cy’inyamaswa, kandi haracyari inzira ndende kugira ngo bibe imiti y’amavuriro, kandi birakenewe ko dushakisha byimazeyo uburyo bwabo bwa farumasi, ingaruka z’uburozi, pharmacokinetics nibindi byinshi.
Urebye inzira ya synthesis, ahanini ishingiye kumuhanda mwiza wa synthesis. Uhereye kubintu byoroshye kandi byoroshye kuboneka ibikoresho fatizo, molekile yintego yubatswe binyuze muburyo bukomeye bwo kubyitwaramo nko kuzunguruka, gusimbuza, no guhuza. Abashakashatsi bahora bagerageza catalizator hamwe nibitangazamakuru byitwara neza, bagahindura ubushyuhe bwibihe, igihe nibindi bihe, kandi bagaharanira kunoza imikorere ya synthesis no kugabanya ibiciro, kugirango harebwe niba bishoboka ko hakurikiranwa ubushakashatsi bwimbitse n’umusaruro w’inganda.


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