Terefone: +86 21 6460 6569
page_banner

ibicuruzwa

4 - [(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile （CAS # 189956-45-4) Ishusho Yerekanwe
  • 4 - [(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile （CAS # 189956-45-4) 1

4 - [(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile （CAS # 189956-45-4)

Umutungo wa Shimi:

Inzira ya molekulari C11H8N4O
Misa 212.21
Ubucucike 1.31 ± 0.1 g / cm3 (Biteganijwe)
Ingingo yo gushonga > 300 ° C.
Ingingo ya Boling 399.7 ° C kuri 760 mmHg
Flash point 195.6 ° C.
Gukemura DMSO (Buhoro), Methanol (Buhoro)
Umwuka 0-0Pa kuri 20-25 ℃
Kugaragara Birakomeye
Ibara Umuhondo wijimye
pKa 8.66 ± 0.40 (Byahanuwe)
Imiterere y'Ububiko 2-8 ° C.
Ironderero 1.67

Ibicuruzwa birambuye

Ibicuruzwa

4 - [(4-Hydroxy-2-pyrimidinyl) amino] benzonitrileCAS #189956-45-4) Amakuru

LogP 0.9 kuri pH6.6
Koresha 4 - [.
kwitegura gupima 2- (methylthio) pyrimidine -4 (3H) -umuntu umwe (3g, 21mmol) na 4-aminobenzonitrile (2.99g, 25mmol) muri flask ya 50mL yo hepfo, irinzwe na azote, ishyuha buhoro kugeza kuri 180 ℃, hanyuma ikora kuri 8 amasaha. Nyuma yo gukonjesha, 20mL ya acetonitrile yongewemo kugirango ivurwe ultrasonic, kuyungurura, cake yo kuyungurura yogejwe na acetonitrile, nta bisigisigi bya aminobenzonitrile 4 byamenyekanye na TLC, kandi bikomeye byumuhondo byoroheje byabonetse mukumisha cake ya filteri ni 4- ( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile n'umusaruro wa 73,6%.
  • Mbere:
  • Ibikurikira:
    • Andika ubutumwa bwawe hano hanyuma utwohereze

    ibicuruzwa bifitanye isano