5-Bromo-2-fluoro-4-methyl-pyridine （CAS # 864830-16-0)
| Kode y'ingaruka | R22 - Byangiza niba byamizwe R37 / 38 - Kurakaza sisitemu yubuhumekero nuruhu. R41 - Ibyago byo kwangirika cyane kumaso |
| Ibisobanuro byumutekano | S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S39 - Kwambara ijisho / kurinda amaso. |
| Icyiciro cya Hazard | IRRITANT |
Intangiriro
Nibintu kama kama hamwe na formula ya molekuline C≡H∞BrFN, ifite atome ya fluor, itsinda rya methyl hamwe na atom ya bromine yasimbujwe impeta ya pyridine.
Kamere:
ni ikintu gikomeye, gifite uburozi kandi kirakaza. Irashobora gushonga mumashanyarazi nka Ethanol na dimethylformamide mubushyuhe bwicyumba, kandi irashobora guhuza hydrogène nabamwe mubakira hydrogène (urugero, alcool).
Koresha:
Bikunze gukoreshwa nkibintu bitangira cyangwa bigereranijwe hagati ya synthesis synthesis. Irashobora gukoreshwa mugutegura imiti, imiti yica udukoko nibindi bintu kama. Ubwinshi bwibikorwa birimo ubushakashatsi bwa farumasi, synthesis ya chimique nibikoresho siyanse.
Uburyo bwo Gutegura:
Uburyo bwo gutegura fluorination burashobora kugerwaho na benzyl bromination na fluorination. Ubwa mbere, urugimbu rwa benzyl (4-methylpyridine) rusubizwa hamwe na benzide ya benzylidene kugirango habeho uruganda rwa bromobenzyl (2-bromo-4-methylpyridine). Uru ruganda noneho rusubizwa hamwe na acide hydrofluoric kugirango itange umusaruro ujyanye na fluor (fosifonium).
Amakuru yumutekano:
ni uburozi, igomba gufata ingamba zikwiye zo kurinda. Irinde guhura n'uruhu, amaso n'inzira z'ubuhumekero mugihe cyo kubaga. Bikwiye gukoreshwa ahantu hafite umwuka mwiza, kandi ukambara ibirahuri bikingira, gants na mask. Ubike kure yumuriro na okiside, kandi wirinde kubyitwaramo nindi miti. Niba ugaragaye cyangwa uhumeka, shaka inama z'ubuvuzi ako kanya.
