5-Trifluoromethyl-pyridine-2-karubasi ya acidemethyl ester (CAS # 124236-37-9)

Methyl 5-trifluoromethylpyridine-2-carboxylate, izwi kandi nka TFP ester, ni ifumbire mvaruganda. Ibikurikira nubusobanuro bwimiterere yabyo, imikoreshereze, imiterere namakuru yumutekano:

Kamere:
-Ibigaragara: amazi adafite ibara
-Imikorere ya molekulari: C8H4F3NO2
-Uburemere bwa molekile: 205.12g / mol
-Ubucucike: 1.374 g / mL
-Icyerekezo: 164-165 ° C.

Koresha:
- TFP esters ikoreshwa cyane muri synthesis organic nubushakashatsi bwa farumasi. Nitsinda ryiza rya aromatic ririnda reagent, rishobora gukoreshwa mukurinda amatsinda ya amino, hydroxyl group hamwe na thioether group.
-Bishobora gukoreshwa nkimiti ya farumasi muguhuza ibice kama birimo amatsinda ya trifluoromethyl.
-Nyongeyeho, ester ya TFP irashobora kandi gukoreshwa muguhuza ibice bya amide, kandi ikoreshwa cyane mubushakashatsi bwimiti, imiti nudukoko twangiza udukoko twangiza ester no kurinda amino.

Uburyo bwo Gutegura:
- TFP esters irashobora gutegurwa mugukora trifluoromethylpyridine hamwe na methyl 2-formate. Ubusanzwe reaction ibera mubushyuhe bwicyumba kandi ibicuruzwa byifuzwa birashobora kwezwa no kubitandukanya.

Amakuru yumutekano:
- TFP ester ifatwa nkumutekano mugihe gisanzwe cyo gukoresha. Ariko, nkibintu kama, bifite akaga runaka.
-Guhuza mu buryo butaziguye uruhu n'amaso birashobora gutera uburakari cyangwa gukomeretsa. Kubwibyo, hakwiye kwitabwaho kwambara ibikoresho bikingira bikingira nka gants na gogles mugihe cyo gukoresha.
-Iyongeyeho, ester ya TFP nayo igomba kuba kure yumuriro nubushyuhe bwinshi kugirango wirinde umuriro cyangwa guturika.

Kubindi bisobanuro byihariye namakuru yumutekano, nyamuneka saba ibitabo bijyanye nimiti cyangwa ubaze umunyamwuga.