alpha-Arbutin （CAS # 84380-01-8)
Ibyago n'umutekano
| WGK Ubudage | 3 |
Amakuru
| Incamake | arbutin ni hydroquinone glycoside ivanze, izina ryimiti ya 4-hydroxyphenyl-d-glucopyranoside (y), ibaho mu mbuto zidubu, bilberry hamwe n’ibindi bimera, ni ibintu bishya bidatera uburakari, bitari allergique, byera byera kandi bifitanye isano ikomeye. Arbutin ifite amatsinda abiri yimikorere kandi ikora mumikorere yayo ya molekile: imwe ni ibisigara bya glucose; Irindi ni hydroxyl ya fenolike. Imiterere yumubiri ya α-arbutin igaragara nkifu yera yera yijimye yijimye, ikabura cyane mumazi na Ethanol. |
| efficacy | α-arbutin ifite ingaruka nziza zo kuvura inkovu zatewe na UV Burns, ifite ingaruka nziza zo kurwanya inflammatory, gusana no kwera. Irashobora guhagarika umusaruro no gushira kwa melanin, ikuraho ibibara na frake. |
| uburyo bwibikorwa | Uburyo bwera bwa α-arbutin burabuza mu buryo butaziguye ibikorwa bya tyrosinase, bityo bikagabanya umusaruro wa melanine, aho kugabanya umusaruro wa melanine uhagarika imikurire ya selile cyangwa imvugo ya tyrosinase. Nkuko α-Arbutin ari ikintu cyiza kandi gifite umutekano cyera cyera, amasosiyete menshi yo kwisiga mu gihugu ndetse no hanze yarwo yakoresheje α-arbutin aho kuba β-arbutine nk'inyongera yera. |
| Gusaba | alpha-Arbutin ni imiti isa na arbutine, irashobora kubuza umusaruro no gushira kwa melanin, ikuraho ibibara na frake. Ibisubizo byerekana ko arbutine ishobora guhagarika ibikorwa bya tyrosinase mukigereranyo gike cyane, kandi ingaruka zayo zo kubuza tyrosinase nibyiza kuruta ibya arbutine. alpha-arbutin irashobora gukoreshwa nkumuzungu wo kwisiga. |
| kwezwa no kumenyekana | icyitegererezo cyabonetse kubisubizo cyakuweho mbere na Ethyl acetate, hanyuma gikurwamo n-butanol, ibyitegererezo byakusanyirijwe hamwe no guhumeka kumashanyarazi azenguruka hanyuma bigashyirwa muri centrifuged. Supernatant yasesenguwe na HPLC igereranwa na chromatogramu ya HPLC ya α-arbutin, niba icyitegererezo na α-arbutin gifite igihe kimwe cyo kugumana cyagereranijwe, kandi niba icyitegererezo kirimo α-Arbutin cyatanzwe mbere. Ibicuruzwa nyuma yo gukuramo no kwezwa byagaragaye nuburyo bwiza bwa ion bwa LC-ESI-MS / MS. Mugereranije misa igereranije yimbuto ya α-idubu nimbuto ya molekile igereranije ya α-arbutin, birashobora kumenyekana niba ibicuruzwa ari α-arbutine. |
| Ikoreshwa | α-arbutin irashobora guhagarika ibikorwa bya tyrosinase mukigereranyo gike ugereranije, ingaruka zayo zo kubuza tyrosinase nibyiza kuruta ibya arbutine |
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