Boc-D-acide acide 4-benzyl ester （CAS # 51186-58-4)

Intangiriro

tert-Butoxycarbonyl-D-acide acide 4-benzyl ester (Boc-D-aspartic aside 4-benzyl ester) ni ifumbire mvaruganda. Ibikurikira nubusobanuro bwimiterere, imikoreshereze, imyiteguro namakuru yumutekano yikigo:

Kamere:

-Ibigaragara: Crystalline yera ikomeye

-Imikorere ya molekulari: C16H21NO6

-Uburemere bwa molekulari: 323.34g / mol

ingingo yo gushonga: 104-106 ℃

-Gukemuka: Gukemura mumashanyarazi asanzwe (nka ether, methanol, etanol)

Koresha:

-tert-Butoxycarbonyl-D-acide acide 4-benzyl ester ikoreshwa cyane nka reagent mubushakashatsi bwibinyabuzima, ikoreshwa muguhuza cyangwa guhindura ibindi bintu kama kama.

-Bikunze gukoreshwa muri synthesis ya peptide nkitsinda ririnda aside aspartique kugirango irinde itsinda ryimikorere kumurongo wa aside amine kandi ikore reaction ya devotection mugihe bikenewe.

Uburyo bwo Gutegura:

-Muri rusange, Boc-D-acide acide 4-benzyl ester itegurwa nigisubizo cya aside aside. Ubwa mbere, acide aspartique ikorwa na acetyl chloride (AcCl) kugirango itange acide acide acide. Acetyl ikingira aspartate acetyl ester noneho ikorwa hamwe na tert-butoxycarbonyl chloride (Boc-Cl) kugirango itange tert-butoxycarbonyl-D-aspartate 4-acetyl ester. Hanyuma, tert-butoxycarbonyl-D-acide acide 4-benzyl ester irashobora kuboneka mugusuzuma inzoga ya benzyl hamwe na base.

Amakuru yumutekano:

- Acide Boc-D-aspartic 4-benzyl ester muri rusange ifite uburozi buke, biracyakenewe gufata ingamba zikwiye zo kubarinda mugihe cyo gukora, nko kwambara uturindantoki, amadarubindi hamwe namakoti ya laboratoire.

-Irinde guhura nuruhu no guhumeka umukungugu.

-Bibike ahantu humye, hakonje, kure yumuriro na okiside.

-Iyo gutunganya no kujugunya, nyamuneka ukurikize inzira zumutekano zikurikizwa.