BOC-GLY-GLY-GLY-OH （CAS # 28320-73-2)

Intangiriro

Tert-Butoxycarbonylglycyl glycylglycine (Boc-Gly-Gly-Gly-OH) ni urugingo ngengabuzima rufite ibintu bikurikira:

Kamere:

-Ibigaragara: mubisanzwe ifu ya kirisiti yera cyangwa ifu ya kristaline

-Imikorere ya molekulari: C17H30N4O7

-Uburemere bwa molekulari: 402.44g / mol

-Gushonga ingingo: hafi 130-132 ° C.

-Gukemuka: Gushonga mumashanyarazi nka dimethylformamide (DMF), dichloromethane, chloroform, nibindi, bidashonga mumazi.

Koresha:

Boc-Gly-Gly-Gly-OH isanzwe ikoreshwa muri synthesis synthesis, cyane cyane kurinda amatsinda cyangwa amatsinda. Irashobora gukoreshwa nkitsinda ririnda aside amine kugirango irinde ingaruka zidasanzwe, kandi ikoreshwa muburyo bukomeye bwa synthesis, peptide synthesis na synthesis.

Uburyo:

Uburyo busanzwe bwo gutegura Boc-Gly-Gly-Gly-OH ni ukumenyekanisha itsinda rya tert-butoxycarbonyl ririnda itsinda rya carboxyl ya glycine. Intambwe zihariye zirimo:

1. Glycine ikorwa hamwe nuruvange rwa sodium nitrite na aside sulfurike kugirango ibone tert-butoxycarbonyl glycinate.

2. Itsinda ririnda Ester ryakuweho na hydrolysis kugirango ibone Boc-glycine.

3. Subiramo intambwe yavuzwe haruguru inshuro ebyiri kugirango winjize carboxyl group ya glycine mumatsinda abiri ya tert-butoxycarbonyl ikingira kugirango ubone Boc-Gly-Gly-Gly-OH.

Amakuru yumutekano:

Gukoresha Boc-Gly-Gly-Gly-OH bigomba kwitondera ibibazo byumutekano bikurikira:

-Irinde guhura n'uruhu n'amaso, kuko bishobora kurakaza uruhu n'amaso.

-Wambare uturindantoki dukingira, amadarubindi n'imyenda ikingira mugihe ukora.

-Korera ahantu hafite umwuka mwiza kugirango wirinde guhumeka umukungugu cyangwa imyuka.

-igomba kubikwa kure yumuriro, ubushyuhe na okiside, komeza kontineri ifunze, ibitswe ahantu hakonje, humye.