Acide Boc-L-glutamic 5-cyclohexyl ester （CAS # 73821-97-3)

Intangiriro

Boc-L-glutamic aside 5-cyclohexyl ester (boc-L-glutamic aside 5-cyclohexyl ester) ni urugimbu. Imiterere yimiti igizwe na tert-butoxycarbonyl (boc) irinzwe L-glutamic acide hamwe na cyclohexanol.

Urusange rufite bimwe mubintu bikurikira:

-Ibigaragara: Ibara ritagira ibara

-Gushonga: hafi dogere selisiyusi 40-45

-Gukemuka: Gushonga mumashanyarazi amwe n'amwe nka dichloromethane, dimethyl sulfoxide na N, N-dimethylformamide, idashonga mumazi.

Uru ruganda rukoreshwa cyane cyane muguhuza ibiyobyabwenge nubushakashatsi bwibinyabuzima, kandi bifite imikoreshereze ikurikira:

-Imikorere ya chimique: Nka groupe irinda aside amine, irashobora kurinda aside glutamic ya synthesis ya polypeptide hamwe na synthesis ikomeye ya synthesis.

-Ubushakashatsi bwibiyobyabwenge: Mubushakashatsi bwibiyobyabwenge, burashobora gukoreshwa mukwiga imiterere-yibikorwa, inzira ya metabolike hamwe nibiyobyabwenge bihamye.

-Ubushakashatsi bwibinyabuzima: bukoreshwa mukwiga uruhare rwa glutamate muri proteyine n'inzira za metabolike.

Gutegura aside ya boc-L-glutamic 5-cyclohexanol ester ikorwa nintambwe zikurikira:

1. Acide L-glutamic ikorwa hamwe na tert-butyl karubone ya aside irinda (nka tert-butoxycarbonyl sodium chloride) kugirango ibone aside boc-L-glutamic.

2. Imyitwarire ya acide boc-L-glutamic hamwe na cyclohexanol ukoresheje ubushyuhe mugihe cya alkaline kugirango ubone aside boc-L-glutamic 5-cyclohexanol ester.

Kubireba amakuru yumutekano yuru ruganda, ingingo zikurikira zigomba kwitonderwa:

-Iyi nteruro irashobora gutera uburakari no kwangiza uruhu, amaso hamwe nubuhumekero. Irinde guhura bitaziguye mugihe cyo gukemura.

-Mu gihe cyo gukora no kubika, irinde guhura na ogisijeni nibintu kama, kuko bishobora kugira ibyago byo okiside no gutwikwa.

-Mu gihe cyo gukoresha, menya neza uburyo bwo guhumeka neza.