BOC-L-Phenylglycine （CAS # 2900-27-8)

Intangiriro

N. Imiterere yacyo irimo itsinda ririnda (itsinda rya Boc), ariryo tsinda rya tert-butoxycarbonyl, rikoreshwa mukurinda reaction yitsinda rya amino.

N-Boc-L-phenylglycine ifite ibintu bikurikira:

- Kugaragara: Crystalline yera ikomeye

- Gukemura: Gukemuka mumashanyarazi amwe, nka dimethylformamide (DMF), dichloromethane, nibindi

N-Boc-L-phenylglycine ikunze gukoreshwa muburyo butandukanye bwo gutera intungamubiri, cyane cyane muguhuza peptide. Itsinda ririnda Boc rishobora kwangizwa nuburyo bwa acide, kugirango itsinda rya amino rishobore gukora hanyuma rigakora reaction nyuma. N-Boc-L-phenylglycine irashobora kandi gukoreshwa nkibikomoka ku kubaka ibigo bya chiral muri synthesis ya peptide.

Gutegura N-Boc-L-phenylglycine bikorwa ahanini nintambwe zikurikira:

Glycine ihindurwamo aside ya benzoic kugirango ibone aside ya benzoic-glycinate ester.

Ukoresheje reaction ya lithium borotrimethyl ether (LiTMP), ester ya benzoic aside-glycinate ester protonone hanyuma ikorana na Boc-Cl (tert-butoxycarbonyl chloride) kugirango ibone N-Boc-L-phenylglycine.

- N-Boc-L-phenylglycine irashobora kurakaza amaso, uruhu, hamwe nubuhumekero kandi bigomba kwirindwa mugihe cyo kuyikoresha.

- Ibikoresho byo kurinda umuntu nka laboratoire ya laboratoire, ibirahure byumutekano, nibindi bigomba kwambarwa mugihe gikora.

- Igomba gukorerwa muri laboratoire ihumeka neza.

- Irinde guhura na okiside na acide ikomeye mugihe ubitse.

- Niba umize cyangwa uhumeka, shaka ubuvuzi bwihuse, uzane ikintu cyikigo, hanyuma utange amakuru yumutekano akenewe kwa muganga.