Boc-L-Tyrosine methyl ester （CAS # 4326-36-7)

Intangiriro

N-Boc-L-Tyrosine Methyl Ester ni imiti ivanga imiti yitwa N-tert-butoxycarbonyl-L-tyrosine methyl ester. Imiterere yacyo niyi ikurikira:

1. Kugaragara: cyera kugeza imvi kristaline ikomeye;

5. Gukemura: gushonga mumashanyarazi kama nka Ethanol na dimethylformamide (DMF), idashonga mumazi.

N-Boc-L-tyrosine methyl ester isanzwe ikoreshwa muri synthesis organique kugirango irinde aside amine muri synthesis ya polypeptide. Bikunze gukoreshwa nkitsinda ririnda L-tyrosine kugirango wirinde ingaruka zidasanzwe mubitekerezo bitabaho. Iyo reaction irangiye, itsinda ririnda rirashobora gukurwaho mubihe bikwiye kugirango ubone ibicuruzwa byiza.

Uburyo bwo gutegura N-Boc-L-tyrosine methyl ester mubusanzwe burimo intambwe zikurikira:

1. Gabanya L-tyrosine muri dimethylformamide (DMF);

2. Ongeramo sodium karubone kugirango ubuze itsinda rya carboxyl ya tirozine;

3. Methanol na methyl karubone (MeOCOCl) byongewe kumvange ya reaction kugirango bitange N-Boc-L-tyrosine methyl ester. Ubusanzwe reaction ikorwa mubushyuhe buke, kandi ikirenga methyl karubone ikoreshwa kugirango reaction ikomeze.

N-Boc-L-tyrosine methyl ester irahagaze neza, ariko iracyakeneye kwitonda. Ibikurikira namakuru yumutekano rusange:

1.

2. Irinde guhumeka: Guhumeka neza bigomba gukorerwa ahantu hakorerwa kugirango hirindwe umwuka uhumeka;

3. Ububiko: Igomba kubikwa ahantu hakonje, humye kandi ukirinda guhura na ogisijeni, aside ikomeye, cyangwa ibishingwe bikomeye.

Muri rusange, N-Boc-L-tyrosine methyl ester ni intera ikomeye hagati ya synthesis organique kandi igira uruhare runini muguhuza peptide. Ugomba kwitondera imikorere itekanye mugihe ukoresha no kuyitunganya.