Boc-N-beta-Trityl-L-asparagine (CAS # 132388-68-2)

Ibisobanuro byumutekano	S22 - Ntugahumeke umukungugu. S24 / 25 - Irinde guhura nuruhu n'amaso.
WGK Ubudage	3
Kode ya HS	2924 29 70
Icyiciro cya Hazard	IRRITANT

NAA-tert-butoxycarbonyl N Γ-trityl aspartamide ni ifumbire mvaruganda, ikunze kuvugwa mu magambo ahinnye Boc-Phe-OtBu. Ifite formula C30H37NO4 kandi ni umweru ukomeye. Kamere:
Boc-Phe-OtBu ni hydrophobique kandi ntishobora gushonga mumazi, ariko irashobora gushonga byoroshye mumashanyarazi nka methanol, Ethanol na dichloromethane. Birasa nkaho bihamye kumurika nubushyuhe.

Koresha:
Boc-Phe-OtBu ikoreshwa cyane cyane mukurinda amatsinda no guhuza ibikorwa muri synthesis. Muri synthesis, irashobora gukoreshwa mukurinda acide aminide acide, muguhuza polypeptide na proteyine, kurinda amatsinda akora kugirango hirindwe ko habaho ingaruka zuruhande. Byongeye kandi, irashobora kandi gukoreshwa mugutegura ibindi bikoresho, nkibiyobyabwenge, amarangi nibikoresho kama.

Uburyo bwo Gutegura:
Gutegura Boc-Phe-OtBu ahanini bikorwa na reaction ya chimique. Uburyo bumwe busanzwe ni ugukora aside p-benzoic hamwe na t-butyl hydroxyformate kugirango itange p-tert-butoxycarbonyl benzoate. Ihita ikorwa na triphenylamine kugirango itange ibicuruzwa byanyuma Boc-Phe-OtBu.

Amakuru yumutekano:
Boc-Phe-OtBu ifite umutekano muke mugukoresha bisanzwe. Nyamara, nkimiti, iracyakeneye kubikwa no gukoreshwa neza. Irinde guhura na okiside ikomeye, irinde guhumeka umukungugu kandi wirinde guhura nuruhu. Mugihe cyo gukoresha, ambara ibikoresho byihariye byo kurinda, nk'uturindantoki n'ibirahure birinda. Mugihe habaye guhura nimpanuka cyangwa kuribwa, shaka inama zubuvuzi ako kanya hanyuma utange umuganga amakuru kubyerekeye imiti. Amategeko y’umutekano y’ibanze agomba gukurikizwa mugihe cyo gutunganya no guta imyanda.