CBZ-D-ALLO-ILE-OH （CAS # 55723-45-0)

Intangiriro

ZD-allo-Ile-OH. DCHA (ZD-allo-Ile-OH · DCHA) ni urugingo ngengabuzima hamwe na reagent yo kurinda aside amine. Ibikurikira nubusobanuro bwimiterere yabyo, imikoreshereze, imiterere namakuru yumutekano:

Kamere:

-Imiti ya chimique: C23H31NO5

-Uburemere bwa molekulari: 405.50g / mol

-Ibigaragara: Crystalline yera ikomeye

-Gushonga: 105-108 ° C.

-Gukemuka: Kubora mumashanyarazi kama nka acetone, ether, dichloromethane, kudashonga mumazi.

Koresha:

- ZD-allo-Ile-OH. DCHA ni reagent ikoreshwa mukurinda aside amine. Mugutangiza itsinda rya Cbz kumatsinda ya amino ya aside amine, guhindura impanuka kumatsinda ya amino mumikorere ya synthesis ya chimique birashobora gukumirwa.

-Bikunze gukoreshwa muri synthesis ya peptide, cyane cyane muguhuza peptide ikurikirana hamwe nuburyo bwihariye cyangwa ibikorwa.

Uburyo bwo Gutegura:

- ZD-allo-Ile-OH. Gutegura DCHA mubisanzwe bitangirira kuri D-isoleucine, hanyuma bigakorana na Cbz anhydride kugirango esterifike itangire itsinda ririnda Cbz. Hanyuma, DCHA (acide dichloroformic) isubizwa hamwe na aside amine kugirango ikore umunyu uhuye.

Amakuru yumutekano:

- ZD-allo-Ile-OH. DCHA ntabwo ari uburozi, ariko igomba gukemurwa neza. Irinde guhura nuruhu namaso, ambara uturindantoki two kurinda hamwe nibirahure nibiba ngombwa.

-Mu gihe cyo gukoresha, uburyo bukoreshwa bwa laboratoire bugomba gukurikizwa kandi hagomba gukoreshwa ibikoresho bihumeka neza.

-Iyo ubitse, shyira ibimera ahantu humye, hakonje kure yumuriro wumuriro numuriro.