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ibicuruzwa

D-1-N-Boc-prolinamide (CAS # 35150-07-3)

Umutungo wa Shimi:

Inzira ya molekulari C10H18N2O3
Misa 214.26
Ubucucike 1.155 ± 0.06 g / cm3 (Biteganijwe)
Ingingo yo gushonga 104-108 ° C.
Ingingo ya Boling 370.1 ± 31.0 ° C (Biteganijwe)
Flash point 177.6 ° C.
Umwuka 1.14E-05mmHg kuri 25 ° C.
Kugaragara Birakomeye
pKa 15.97 ± 0.20 (Biteganijwe)
Imiterere y'Ububiko Komeza ahantu hijimye, Gufunzwe byumye, Ubushyuhe bwicyumba
Ironderero 1.504
MDL MFCD00190827

Ibicuruzwa birambuye

Ibicuruzwa

Ibimenyetso bya Hazard Xn - Byangiza
Kode y'ingaruka 22 - Byangiza iyo bimizwe
Ibisobanuro byumutekano 24/25 - Irinde guhura nuruhu n'amaso.
WGK Ubudage 2

 

Intangiriro

D-1-N-Boc-prolinamide (D-1-N-Boc-prolinamide) ni urugingo ngengabuzima rufite ibintu bikurikira:

 

1. Kugaragara: Crystalline yera ikomeye.

2. Inzira ya molekile: C14H24N2O3.

3. Uburemere bwa molekuline: 268.35g / mol.

4. Gushonga ingingo: hafi dogere selisiyusi 75-77.

5. Gukemura: Kubora mumazi hamwe na solge zimwe na zimwe, nka chloroform, Ethanol na dimethyl sulfoxide.

 

Bumwe mu buryo bukoreshwa bwa D-1-N-Boc-prolinamide ni nka chiral reagent ya sintezime ya asimmetrike muri synthesis ya chimique organic. Irashobora gukoreshwa nk'inyubako ya skelet ya chiral kugirango imenyekanishe amakuru ya chiral binyuze muri chiral center yayo, bityo ubone chiral compound. Byongeye kandi, irashobora kandi gukoreshwa nkigihe cyo guhuza ibiyobyabwenge, imiti yica udukoko hamwe na molekile ya bioactive.

 

Uburyo bwo gutegura D-1-N-Boc-prolinamide mubusanzwe ni ugukora N-Boc-L-proline hamwe na tert-butyl chloroformate mubihe bya alkaline kugirango habeho hagati ya N-Boc-L-proline methyl ester, hanyuma ukavura ubushyuhe kuri kubyara ibicuruzwa bigenewe.

 

Kubyerekeranye namakuru yumutekano, ubushakashatsi burambuye bwuburozi ni D-1-N-Boc-prolinamide ibura. Nyamara, muri rusange, ibikorwa byumutekano bya laboratoire bigomba gukurikizwa, kandi ingamba zo gukingira nka gants, indorerwamo n imyenda ikingira bigomba kwitabwaho mugihe ukoresheje. Byongeye kandi, igomba kubikwa mu kintu gifunze kugirango wirinde guhura na ogisijeni nubushuhe. Niba uhumeka kubwimpanuka cyangwa uhuye nuruhu n'amaso, kwoza ako kanya n'amazi menshi hanyuma ushakire ubuvuzi. Niba imyanda igomba gutabwa, hagomba gukurikizwa amabwiriza yaho. Nibyiza gukoresha no gutunganya uruganda ruyobowe numuntu ufite ubumenyi bwumwuga muri chimie.


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