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D-Glutamine （CAS # 5959-95-5) Ishusho Yerekanwe
  • D-Glutamine （CAS # 5959-95-5) 1

D-Glutamine （CAS # 5959-95-5)

Umutungo wa Shimi:

Inzira ya molekulari C5 H10 N2 O3
Misa 146.14
Ubucucike 1.3394 (igereranya)
Ingingo yo gushonga 184-185 ° C.
Ingingo ya Boling 265,74 ° C (igereranya)
Guhinduranya byihariye (α) -32 º (589nm, c = 10, N HCl)
Amazi meza 42.53g / L (ubushyuhe ntibuvuzwe)
Gukemura Gushonga mumazi (9 mg / ml kuri 25 ° C), DMSO (<1 mg / ml kuri 25 ° C), na Ethanol (<1 mg / m
Kugaragara Ifu ya kirisiti yera
Ibara Cyera
BRN 1723796
pKa 2.27 ± 0.10 (Biteganijwe)
Imiterere y'Ububiko Komeza ahantu hijimye, Inert ikirere, Ubushyuhe bwicyumba
Ironderero -33 ° (C = 5, 5mol / LH
MDL MFCD00065607
Ibintu bifatika na shimi Ingingo yo gushonga: 185
Mu bushakashatsi bwa vitro Glutamine ni aside amine yingenzi muri sisitemu yo hagati (CNS), igira uruhare runini muri glutamate / GABA-Glutamine cycle (GGC). Muri GGC, Glutamine yimurwa ivuye muri astrocytes ikajya muri neuron, aho izuzuza ibizenga bya neurotransmitter. D-Glutamine yakoreshejwe mu kwiga uruhare rwayo mu kurinda umutekano wa acetaldehyde iterwa no guhagarika imikorere ya bariyeri muri monolayeri ya Caco-2. Uruhare rwa L-Glutamine mu kurinda epitelium yo mu mara kwirinda acetaldehyde iterwa no guhagarika imikorere ya barrière isuzumwa muri monolayeri ya Caco-2. L-Glutamine yagabanije igabanuka rya acetaldehyde iterwa no kugabanuka kwamashanyarazi ya transepithelilal no kongera ubushobozi bwa inuline na lipopolysaccharide mugihe- kandi biterwa na dose; D-Glutamine, L-aspargine, L-arginine, L-lysine, cyangwa L-alanine nta kurinda gukomeye. D-Glutamine inanirwa guhindura igabanuka rya acetaldehyde iterwa na TER no kwiyongera kwa inuline. D-Glutamine cyangwa glutaminase inhibitor yonyine ntabwo byagize ingaruka kuri TER cyangwa inulin flux mugucunga cyangwa acetaldehyde ivurwa na selile monolayers. Kutagira ingaruka za D-Glutamine mukurinda acetaldehyde byerekana ko kurinda L-Glutamine kwunganirwa ari stereospecific.

Ibicuruzwa birambuye

Ibicuruzwa

Ibimenyetso bya Hazard Xi - Kurakara
Kode y'ingaruka 36/37/38 - Kurakaza amaso, sisitemu yubuhumekero nuruhu.
Ibisobanuro byumutekano S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso.
S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi.
S27 - Kuramo ako kanya imyenda yose yanduye.
S24 / 25 - Irinde guhura nuruhu n'amaso.
WGK Ubudage 3
Kode ya HS 29241900

 

Intangiriro

Isomer idasanzwe ya glutamine mubyukuri ntishobora gukomera muri methanol, Ethanol, ether na benzene.

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