Ethyl cyanoacetate (CAS # 105-56-6)
Ibimenyetso bya Hazard | Xi - Kurakara |
Kode y'ingaruka | R36 / 38 - Kurakaza amaso n'uruhu. |
Ibisobanuro byumutekano | S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S37 / 39 - Kwambara uturindantoki dukwiye no kurinda amaso / kurinda amaso |
Indangamuntu ya Loni | UN 2666 |
Ethyl cyanoacetate (CAS # 105-56-6) Intangiriro
Ethyl cyanoacetate, CAS numero 105-56-6, nibikoresho byingenzi bya chimique.
Mu buryo bwubaka, ikubiyemo itsinda rya cyano (-CN) hamwe nitsinda rya estyl ester (-COOCH₂CH₃) muri molekile yaryo, kandi uku guhuza imiterere ituma imiti itandukanye. Kubijyanye nimiterere yumubiri, mubisanzwe ni ibara ritagira ibara ryumuhondo ryoroshye rifite impumuro idasanzwe, aho gushonga nka -22.5 ° C, ahantu ho gutekera hagati ya 206 - 208 ° C, gushonga mumashanyarazi kama nka alcool na ethers, hamwe no gukomera kwamazi ariko ugereranije ni nto.
Kubijyanye nimiterere yimiti, polarite ikomeye yitsinda rya cyano hamwe nibiranga esterification biranga itsinda rya Ethyl ester byerekana ko ishobora guhura nibibazo byinshi. Kurugero, ni nucleophile classique, kandi itsinda rya cyano rishobora kwitabira reaction ya Michael, kandi hamwe na conjugation hamwe na α, β-karubone yuzuye ya karubone irashobora gukoreshwa mukubaka imigozi mishya ya karubone-karubone, itanga inzira nziza kuri synthesis ya molekile igoye. Amatsinda ya Ethyl ester arashobora guhindurwa hydrolyz mugihe cya acide cyangwa alkaline kugirango ibe acide ya carbokisike ihuye, ningirakamaro muguhindura amatsinda akora muri synthesis organique.
Kubijyanye nuburyo bwo gutegura, Ethyl chloroacetate na sodium cyanide ikoreshwa nkibikoresho fatizo kugirango bitegure binyuze mu gusimbuza nucleophilique, ariko iki gikorwa gikeneye kugenzura byimazeyo dosiye nigisubizo cya sodium cyanide, kubera uburozi bukabije nigikorwa kidakwiye, biroroshye guteza impanuka z'umutekano, kandi birakenewe kandi kwitondera ingamba zo gukurikirana isuku kugirango ubone ibicuruzwa bifite isuku nyinshi.
Mu nganda zikoreshwa mu nganda, ni urufunguzo rwo hagati mu guhuza imiti myiza nka farumasi, imiti yica udukoko, n'impumuro nziza. Mu buvuzi, ikoreshwa mu gukora imiti igabanya ubukana nka barbiturates; Mu rwego rw’imiti yica udukoko, witabire guhuza ibice hamwe nudukoko twica udukoko twica udukoko; Muri synthesis yimpumuro nziza, irashobora kubaka skeleton ya molekile idasanzwe kandi ikanatanga ibikoresho fatizo bidasanzwe byo kuvanga uburyohe butandukanye, bigira uruhare runini mugushigikira inganda zigezweho, ubuhinzi ninganda zikoreshwa mubicuruzwa.
Twakagombye gushimangira ko kubera itsinda rya cyano, Ethyl cyanoacetate ifite uburozi ningaruka zimwe na zimwe kuruhu, amaso, inzira zubuhumekero, nibindi, bityo rero birakenewe kwambara ibikoresho birinda ahantu hashobora guhumeka neza mugihe cyo gukora, kandi gukurikiza byimazeyo amabwiriza yumutekano ya laboratoire yimiti nogukora imiti.