FMOC-D-ALLO-ILE-OH (CAS # 118904-37-3)

N-fluorenexyxycarbonyl-D-allisoleucine, ikomoka kuri aside amine. Imiterere yacyo niyi ikurikira:

Kugaragara: Fmoc-allisoleucine ni ifu yera cyangwa umuhondo ifu ya kristaline.
Gukemura: Ifite imbaraga zo gukemura neza mumashanyarazi nka dimethyl sulfoxide (DMSO) na chloride methylene.

Synthesis ya fonctionnement ikomeye: Mubisanzwe ikoreshwa nkibikoresho fatizo bya synthesis ikomeye ya polypeptide, kandi iminyururu ya polypeptide yubatswe no gukomeza kongeramo andi acide amine.
Ubushakashatsi bukoresha: Bikunze gukoreshwa mukwiga ahantu nka proteine ​​imiterere, imikorere, n'imikoranire.

Uburyo bwo gutegura FMOC-allisoleucine burimo ahanini intambwe zikurikira:

N-fluorenylmethionine isubizwa hamwe nabakora nka dithioethylcarbamate na N, N'-dicyclohexylcarbodiimide kugirango babone N-fluorenylmethoxycarbonyl-D-allisoleucine.
Iyo reaction irangiye, gutandukana no kwezwa bikorwa kugirango ubone ibicuruzwa bigenewe.

Birashobora kugira ingaruka mbi kuri sisitemu yubuhumekero nuruhu, kandi ingamba zikwiye nko kwambara ubuhumekero hamwe na gants zo gukingira bigomba gufatwa mugihe cyo kubaga.
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