Fmoc-D-Cyclohexyl glycine （CAS # 198543-96-3)

Umutungo wa Shimi:

Inzira ya molekulari	C23H25NO4
Misa	379.45
Ubucucike	1.238
Ingingo yo gushonga	161-187 ℃
Ingingo ya Boling	602.9 ± 38.0 ° C (Biteganijwe)
Kugaragara	Ifu yera kugeza yera
pKa	3.89 ± 0.10 (Byahanuwe)
Imiterere y'Ububiko	Ikidodo cyumye, Ubushyuhe bwicyumba

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Fmoc-D-Cyclohexyl glycine （CAS # 198543-96-3) Amakuru

Koresha

Fluorene mikorerexycarbonyl D-cyclohexylglycine ni imiti isanzwe yimiti nubumara, chloride ya fluorenyl (FMOC-Cl) ni chloroformate. Ikoreshwa mugukora fluorene mikorerexycarbonyl (itsinda rya FMOC) muri fluore methoxycarbonyl carbamate karbamate ya FMOC, nitsinda risanzwe ririnda amino.

Kwitegura

Synthesis ya fluorenexyxycarbonyl D-cyclohexylglycine yavuzwe mubitabo. Ukoresheje cyclohexyl bromide nkibikoresho fatizo, imbere ya sodium alkoxide, ihura na alkylation reaction hamwe na diethyl malonate, hanyuma hydrolyzes, acide, na decarboxylates kugirango ibone aside irike ya cyclohexyl; ibya nyuma noneho bromine na ammonolysis DL-Cyclohexylglycine; amaherezo, reaction ya acylation ibaho imbere ya fluorène vitxycarbonyl chloride kugirango ibone fluore methoxycarbonyl D-cyclohexylglycine [1]. Inzira ya synthesis inzira niyi ikurikira:

Mbere: AC-TYR-NH2 （CAS # 1948-71-6)

Ibikurikira: 2-Amino-4-bromobenzoic aside （CAS # 20776-50-5)

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