Fmoc-L-2-Aminobutyric aside (CAS # 135112-27-5)

Ibisobanuro byumutekano	S22 - Ntugahumeke umukungugu. S24 / 25 - Irinde guhura nuruhu n'amaso.
WGK Ubudage	3
Kode ya HS	2924 29 70
Icyiciro cya Hazard	IRRITANT

L-2- (fluorenylmethoxycarbonylamino) acide butyric, izwi kandi nka aside Fmoc-glutamic (L-2- (9-fluorenylmethoxycarbonylamino) acide butyric), ni ibintu kama. Ibikurikira nubusobanuro bwa bimwe mubiranga, imikoreshereze, uburyo namakuru yumutekano:

Kamere:
-Ibigaragara: Ifu idafite ibara ry'umuhondo cyangwa umuhondo muto;
-Imikorere ya molekulari: C26H23NO4;
-Uburemere bwa molekulari: 413.47g / mol;
-gushonga ingingo: hafi 166-168 ℃;
-Gukemuka: Acide Fmoc-glutamic irashonga mumashanyarazi kama nka dimethylformamide na aside hydrofluoric.

Koresha:
Acide Fmoc-glutamic, nkurwego rwo gukingira itsinda, ikoreshwa kenshi muri synthesis ya peptide, cyane cyane muguhuza peptide ihamye hamwe no guhuza peptide ya Levenstein (peptide ya Levenshtein). Irashobora gukoreshwa nkurwego rwo hagati ya acide ya amino, cyangwa ikoreshwa muguhuza icyiciro gikomeye, imikorere ya chromatografiya ikora cyane, nibindi.

Uburyo bwo Gutegura:
Gutegura aside Fmoc-glutamic muri rusange harimo intambwe zikurikira:
1.
2. Kubwumunyu wa aside Fmoc-glutamic, ushonga mumashanyarazi (nka dimethylformamide) hanyuma ugakoreshwa muburyo bukwiye bwo kwezwa (nka kristu) kugirango ubone aside Fmoc-glutamic.

Amakuru yumutekano:
Acide Fmoc-glutamic isanzwe ihagaze neza kandi ifite uburozi buke mubikorwa bisanzwe. Ariko nkibintu kama, biracyakenewe kwitondera ingamba zikurikira z'umutekano:
-Irinde guhumeka umukungugu, guhura nuruhu n'amaso;
-Mu gihe cyo gukora, kwambara uturindantoki turinda, ibirahure n'imyambaro ikingira yujuje ibyangombwa bisabwa;
-Korera ahantu hafite umwuka uhagije kugirango wirinde guhura nigihe kirekire;
-Niba imyanda iva muri iki kigo igomba kujugunywa, igomba kujugunywa neza hakurikijwe amabwiriza y’ibanze.