Fmoc-L-homophenylalanine (CAS # 132684-59-4)
Ibyago n'umutekano
| Ibimenyetso bya Hazard | Xi - Kurakara |
| Kode y'ingaruka | 36/37/38 - Kurakaza amaso, sisitemu yubuhumekero nuruhu. |
| Ibisobanuro byumutekano | S22 - Ntugahumeke umukungugu. S24 / 25 - Irinde guhura nuruhu n'amaso. S44 - S35 - Ibi bikoresho hamwe nibikoresho byabyo bigomba gutabwa muburyo bwiza. S28 - Nyuma yo guhura nuruhu, oza ako kanya ukoresheje amasabune menshi. S7 - Komeza ibikoresho bifunze cyane. S4 - Irinde aho uba. |
| WGK Ubudage | 3 |
| Kode ya HS | 2924 29 70 |
| Icyiciro cya Hazard | IRRITANT |
Intangiriro
2. Gukemura: Gushonga mumashanyarazi nka dimethyl sulfoxide (DMSO) na Ethyl acetate (EtOAc), idashonga mumazi.
3. Inzira ya molekile: C32H29NO4.
4. Uburemere bwa molekile: 495.58.
Imikoreshereze nyamukuru ya Fmoc-L-homophenylalanine ni nkitsinda ririnda peptide. Fmoc ni impfunyapfunyo ya furoyl n'ibiyikomokaho, bishobora kurinda itsinda rya amino muri aside amine. Iyo byifujwe guhuza urunigi rwa peptide, itsinda rya amino rirashobora kuboneka kubisubizo mugukuraho itsinda ririnda Fmoc. Kubwibyo, Fmoc-L-homophenylalanine igira uruhare runini mugutegura imiti ya peptide na molekile zijyanye na bioactive.
Uburyo bwo gutegura Fmoc-L-homophenylalanine buragoye kandi burimo intambwe yintambwe nyinshi. Uburyo busanzwe bwo kwitegura nuburyo bwo gufatanya na Fmoc irinzwe na fenilalanine hamwe nizindi reagent, nka silver azide formate (AgNO2), hagakurikiraho kuvura aside trifluoroacetic guha Fmoc-L-homophenylalanine.
Amakuru yumutekano akurikira agomba kwitonderwa mugihe ukoresheje Fmoc-L-homophenylalanine:
1. Irinde guhura bitaziguye nuruhu, amaso hamwe nuduce twinshi, kuko bishobora kurakaza umubiri wumuntu.
2. Ububiko bugomba kwirinda guhura na okiside ikomeye cyangwa acide ikomeye kugirango wirinde ingaruka mbi.
3.
4. Ibikorwa byose bigomba gukorwa mugihe cya laboratoire ihumeka neza.
Muri make, Fmoc-L-homophenylalanine nitsinda ririnda aside amine ikunze gukoreshwa muri synthesis ya peptide kandi ifite uburyo bwinshi bwo kuyikoresha. Mugihe ukoresha no gutunganya uruganda, birakenewe kwitondera gufata neza no kubika.
