Fmoc-O-tert-butyl-L-tyrosine （CAS # 71989-38-3)
| Ibimenyetso bya Hazard | Xi - Kurakara |
| Kode y'ingaruka | 36/37/38 - Kurakaza amaso, sisitemu yubuhumekero nuruhu. |
| Ibisobanuro byumutekano | S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S24 / 25 - Irinde guhura nuruhu n'amaso. |
| WGK Ubudage | 3 |
| Kode ya HS | 2924 29 70 |
Intangiriro
Fluorene mikorerexycarbonyl-oxotert-butyl-tyrosine ni imiti ivanga imiti ikunze kwitwa FMOC-Tyr (tBu) -OH. Ibikurikira nintangiriro yimiterere yabyo, imikoreshereze, imyiteguro namakuru yumutekano:
Ubwiza:
- Kugaragara: Umweru cyangwa utari umweru ukomeye.
- Gukemura: Gukemuka mumashanyarazi amwe n'amwe, nka dimethyl sulfoxide na dimethylformamide.
Koresha:
- Kurinda amatsinda muri synthesis ya chimique: Amatsinda ya FMOC arashobora gukoreshwa mukurinda amatsinda ya amino mubice bya fenolike kugirango birinde gukora. FMOC-Tyr (tBu) -OH irashobora gukoreshwa nkibikoresho byo gutangiza iminyururu ya peptide muri synthesis.
Uburyo:
Uburyo bwo gutegura FMOC-Tyr (tBu) -OH bushobora kugerwaho nintambwe zikurikira:
- Fluorenyl chloride (FMOC-Cl) isubizwa hamwe na tert-butyl (tBu-NH2) kugirango itange fluorenylmethoxycarbonyl-tert-butichsyl (FMOC-tBu-NH-).
- Noneho, reba ibisubizo bya FMOC-tBu-NH- hamwe na tyrosine (Tyr-OH) kugirango ubyare FMOC-Tyr (tBu) -OH.
Amakuru yumutekano:
- Gukoresha FMOC-Tyr (tBu) -OH bigomba kubahirizwa na protocole yumutekano wa laboratoire.
- Irinde guhura nuruhu n'amaso, kandi wambare uturindantoki two kurinda hamwe na gogles mugihe ukoresha.
- Koresha ahantu hafite umwuka mwiza, kure yumuriro no gutwikwa.
- Ntigomba kurekurwa mu bidukikije kandi igomba gukemurwa no kujugunywa hakurikijwe amabwiriza y’ibanze.
