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L-Pyroglutamic aside CAS 98-79-3

Umutungo wa Shimi:

Inzira ya molekulari C5H7NO3
Misa 129.11
Ubucucike 1.3816 (igereranya)
Ingingo yo gushonga 160-163 ° C (lit.)
Ingingo ya Boling 239.15 ° C (igereranya)
Guhinduranya byihariye (α) -27.5 º (c = 10, 1 N NaOH)
Flash point 227.8 ° C.
Amazi meza 10-15 g / 100 mL (20 ºC)
Gukemura Gushonga mumazi, inzoga, acetone na acide glacial acetike, gushonga gato muri Ethyl acetate, kudashonga muri ether.
Umwuka 0.002Pa kuri 25 ℃
Kugaragara Kirisiti nziza
Ibara Cyera kugeza cyera
Merk 14.8001
BRN 82132
pKa 3.32 (kuri 25 ℃)
PH 1.7 (50g / l, H2O, 20 ℃)
Imiterere y'Ububiko 2-8 ° C.
Igihagararo Ihamye. Ntibishobora kubangikanya, acide, ibintu bikomeye bya okiside.
Ironderero -10 ° (C = 5, H2O)

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Ibyago n'umutekano

Ibimenyetso bya Hazard Xi - Kurakara
Kode y'ingaruka 36/37/38 - Kurakaza amaso, sisitemu yubuhumekero nuruhu.
Ibisobanuro byumutekano S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi.
S36 - Kwambara imyenda ikingira.
S37 / 39 - Kwambara uturindantoki dukwiye no kurinda amaso / kurinda amaso
WGK Ubudage 3
RTECS TW3710000
FLUKA BRAND F CODES 21
TSCA Yego
Kode ya HS 29337900
Icyiciro cya Hazard IRRITANT

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Erekana byinshi
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Amakuru y'ibanze

okiside protine nayo izwi nkaL-pyroglutamic aside. Imisemburo ya molekile igereranije 129.12. Ingingo yo gushonga yari 162-163 ° c. Ntugashonga muri ether, Ethyl acetate-soluble, gushonga mumazi (25 ° C 40), Ethanol, acetone na acide acike. Guhinduranya optique yihariye -11.9 ° (c = 2, H2O). Umunyu wa sodiumi urashobora gukoreshwa nkigikoresho cyo kwisiga mu kwisiga, ingaruka zacyo zitanga amazi meza kuruta glycerol, sorbitol, idafite uburozi, nta ngaruka zikangura, mu kwita ku ruhu no kwisiga umusatsi; Iki gicuruzwa kigira ingaruka mbi kuri okiside ya tyrosine, irashobora gukumira iyimikwa rya melanine, igira ingaruka yera kuruhu; Ifite ingaruka yoroshye kuruhu, irashobora gukoreshwa mumavuta yo kwisiga; Irashobora kandi gukoreshwa nka surfactant kumashanyarazi; Imiti yimiti, kugirango ikemure amine yubwoko; Abahuza kama.

 

Intangiriro aside pyroglutamic ni 5-oxyproline. Ikorwa no kubura umwuma hagati yitsinda α-NH2 na γ-hydroxyl groupe ya acide glutamic kugirango ibe umusemburo wa lactam; Irashobora kandi gushingwa mugutakaza itsinda rya Amido muri molekile ya glutamine. Niba glutathione synthetase ibuze, irashobora gutera pyroglutamemia, urukurikirane rwibimenyetso byubuvuzi. Pyroglutamemia ni indwara ya metabolisme ya aside iterwa no kubura glutathione synthetase. Kugaragara kwa Clinical kuvuka amasaha 12 ~ 24 yo gutangira, hemolysis igenda itera imbere, jaundice, Acidose ya Metabolic idakira, indwara zo mumutwe, nibindi.; Inkari zirimo aside pyroglutamic, aside ya lactique, Alpha deoxy4 lipide aside glycoloacetic. Kuvura, ibimenyetso, witondere guhindura imirire nyuma yimyaka.
imitungo L-pyroglutamic aside, izwi kandi nka L-pyroglutamic aside, L-pyroglutamic. Uhereye kuri Ethanol na peteroli ivangwa na ether mu mvura yimvura ya orthorhombic idafite cone Crystal, gushonga ya 162 ~ 163 ℃. Gushonga mumazi, inzoga, acetone na acide acike, Ethyl acetate-soluble, idashonga muri ether. Guhinduranya optique yihariye -11.9 ° (c = 2, H2O).

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