Methoxymethyl triphenylphosphonium chloride （CAS # 4009-98-7)
Intangiriro
Gukoresha
(Methoxymethyl) triphenylphosifore chloride ikoreshwa muguhuza cefaltacine, ikaba ari imiti igabanya ubukana kandi irwanya ibibyimba. Irakoreshwa kandi mugushushanya igice cya paclitaxel.
Kwitegura
Uburyo bwo guhuza (mikorerexymethyl) triphenylphosifore chloride, igizwe nintambwe zikurikira: mukurinda azote, kongeramo 50mL ya acetone ya anhydrous muri reaction, hanyuma ukongeramo 32g ya triphenylphosifine, ukabyutsa kandi ukazamura ubushyuhe kuri 37 ° C, bikomeza ubushyuhe buhoraho , wongeyeho 20g ya methyl chloromethyl ether kuri reaction, hanyuma ukabyitwaramo kuri 37 ° C kuri 3h, ukazamura buhoro buhoro ubushyuhe kuri 47 ° C ku gipimo cya 1 ° C / min, reaction yarakomeje kuri 3h, reaction irahagarara, kandi 37.0g (methoxymethyl) triphenylphosifore chloride yabonetse hakoreshejwe kuyungurura, ether anhydric yoza no gukama hamwe n'umusaruro wa 88.5%.
