N-Boc-N'-tosyl-D-histidine （CAS # 69541-68-0)

Intangiriro

Boc-D-Ibye (Tos) -OH (Boc-D-His (Tos) -OH) ni imiti ifite imiti ikurikira:

Kamere:

1. Kugaragara: umweru ukomeye

2. Inzira ya molekile: C21H25N3O6S

3. Uburemere bwa molekile: 443.51

4. Ingingo yo gushonga: hafi 110-115 ° C.

Koresha:

Boc-D-Ibye (Tos) -OH isanzwe ikoreshwa muri synthesis organique nkitsinda ririnda D-histidine (D-His). Imikoreshereze yacyo nyamukuru irimo:

1. Muri synthesis ya polypeptide, ikoreshwa muguhuza urukurikirane rwa polypeptide irimo itsinda ririnda D-histidine.

2. Byakoreshejwe nkumuhuza murwego rwa chimie yubuvuzi kugirango uhuze ibinyabuzima bikora neza.

3. Gushushanya no guhuza ibice byabakandida ibiyobyabwenge mubushakashatsi.

Uburyo bwo Gutegura:

Gutegura Boc-D-We (Tos) -OH mubusanzwe bikorwa nintambwe zikurikira:

1.

2. Mubihe bya alkaline, D-His-Tos yakiriwe na n-butoxycarbonylhydrazine (tert-butyloxycarbonylhydrazide) kugirango itange Boc-D-His (Tos) -OH.

Amakuru yumutekano:

Isuzuma ryumutekano rya Boc-D-His (Tos) -OH ni ntarengwa, ariko nkibintu byimiti, hagomba kwitonderwa ibitekerezo byumutekano bikurikira:

1. Irinde guhumeka, guhura nuruhu n'amaso. Wambare ibikoresho bikingira umuntu ku giti cye, nk'uturindantoki n'ibirahure.

2. Uburyo bwiza bwa laboratoire bugomba gukurikizwa mugihe cyo gukoresha kandi hagomba kubaho uburyo bwiza bwo guhumeka.

3. Bika mu kintu gifunze, kure yumuriro na okiside.

4. Kurikiza amabwiriza n'amabwiriza bijyanye mugihe cyo gutunganya.

Mugihe ukoresheje Boc-D-We (Tos) -OH, nyamuneka wemeze gukurikiza amabwiriza yumutekano ya laboratoire hamwe namabwiriza yo gukora, kandi ubike neza kandi ukore imiti. Nibiba ngombwa, birasabwa gukora iyobowe nababigize umwuga.