N-Boc-N'-trityl-L-glutamine (CAS # 132388-69-3)

WGK Ubudage	3
Kode ya HS	29242990

N-Boc-N '-trityl-L-glutamine (N-Boc-N'-trityl-L-glutamine, mu magambo ahinnye yitwa Boc-Gln (Trt) -OH) ni ifumbire mvaruganda. Ifite ibintu bikurikira: 1. Kugaragara: ifu ya kirisiti yera.
2. Inzira ya molekile: C39H35N3O6
3. Uburemere bwa molekuline: 641.71g / mol
4. Ingingo yo gushonga: 148-151 ° C.
5. Gukemura: Gukemuka mumashanyarazi menshi, nka dimethyl sulfoxide (DMSO) na dichloromethane.
6. Guhagarara: ugereranije bihamye mubihe bisanzwe byubushakashatsi.

Muri synthesis ya chimique, N-Boc-N '-trityl-L-glutamine ikoreshwa kenshi nka aside amine irinda itsinda cyangwa hagati. Imikoreshereze yacyo nyamukuru irimo:

1. Ikoreshwa nka glutamine irinda itsinda muri peptide na synthesis.
2. Mu bushakashatsi bwibiyobyabwenge byubukorikori, bikoreshwa muguhuza glutamine.
3. Byakoreshejwe nkigihe cyo guhuza ibindi bintu kama.

Uburyo bwo gutegura N-Boc-N '-trityl-L-glutamine muri rusange nuburyo bukurikira:

1. Ubwa mbere, reba glutamine N irinzwe (nka N-Boc-L-glutamine) hamwe na trityl halide (nka trityl chloride) kugirango ubone N-Boc-N '-trityl-L-glutamine.

Amakuru yumutekano:
N-Boc-N '-trityl-L-glutamine, nkibintu kama kama, bifite umutekano muke kubikoresha neza no kubika. Ariko, ibibazo bikurikira biracyakenewe kwitonderwa:

1. Irinde guhura n'amaso, uruhu n'inzira z'ubuhumekero. Koresha uturindantoki two kurinda imiti hamwe na gogles.
2. Ubike ahantu humye, hakonje.
3. Kurikiza inzira zumutekano kandi ukore neza kandi ujugunye imyanda yikigo.