N-Cbz-L-Leucine （CAS # 2018-66-8)
Ibyago n'umutekano
| Ibimenyetso bya Hazard | Xn - Byangiza |
| Kode y'ingaruka | R10 - Yaka R20 / 22 - Byangiza muguhumeka kandi niba byamizwe. R37 / 38 - Kurakaza sisitemu yubuhumekero nuruhu. R40 - Ibimenyetso bike byerekana ingaruka ziterwa na kanseri R41 - Ibyago byo kwangirika cyane kumaso R36 / 37/38 - Kurakaza amaso, sisitemu y'ubuhumekero n'uruhu. R20 / 21/22 - Byangiza muguhumeka, guhura nuruhu kandi niba byamizwe. R67 - Imyuka irashobora gutera gusinzira no kuzunguruka R63 - Ibyago bishobora kugirira nabi umwana utaravuka R19 - Irashobora gukora peroxide iturika |
| Ibisobanuro byumutekano | S16 - Irinde amasoko yo gutwikwa. S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso. S45 - Mugihe habaye impanuka cyangwa niba wumva utameze neza, shaka inama zubuvuzi ako kanya (erekana ikirango igihe cyose bishoboka.) S36 - Kwambara imyenda ikingira. S36 / 37 - Wambare imyenda ikingira hamwe na gants. S60 - Ibi bikoresho hamwe nibikoresho byabyo bigomba gutabwa nkimyanda ishobora guteza akaga. |
| Indangamuntu ya Loni | UN 1993 3 / PG 3 |
| WGK Ubudage | 3 |
| RTECS | OH2921000 |
| Kode ya HS | 29242990 |
N-Cbz-L-Leucine （CAS # 2018-66-8) intangiriro
Cbz-L-leucine, izina ryuzuye rya Boc-L-leucine (Boc bisobanura itsinda ririnda dibutoxycarbonyl), ni inkomoko ya aside amine. Ibikurikira nintangiriro yimiterere yabyo, imikoreshereze, uburyo bwo gukora namakuru yumutekano:
Ubwiza:
- Kugaragara: Crystalline yera ikomeye
- Gukemura: Gukemura muri Ethanol, dimethylformamide (DMF) na dichloromethane
Koresha:
- CBZ-L-Leucine nitsinda rikoreshwa cyane ririnda aside amine irinda hydroxyl groupe ya leucine mugihe cyo guhuza peptide kugirango irinde kwifata nizindi reaction. Muri synthesis ya peptide aho hagomba gutangizwa ibisigazwa byinshi bya leucine, Cbz-L-leucine irashobora gukoreshwa mukurinda hydroxyl groupe ya leucine kugirango ikorwe nyuma.
- Leucine ni aside amine y'ingenzi igira uruhare runini mu miterere ya poroteyine n'imikorere.
Uburyo:
- Gutegura Cbz-L-leucine mubisanzwe tubonwa nigisubizo cya leucine hamwe na Boc-OSu (Boc - N-nitrocarbonyl-L-leucine). Mubisubizo, Boc-OSu ikora nkintangiriro yitsinda ririnda kandi ikagira esterification reaction hamwe na leucine kugirango itange Cbz-L-leucine.
Amakuru yumutekano:
- Cbz-L-leucine ni imiti kandi igomba kubikwa neza kure yumuriro na okiside.
- Mugihe cyo gukoresha, irinde guhumeka umukungugu wacyo cyangwa guhura nuruhu namaso.
- Kurikiza imyitozo yumutekano ijyanye no gutunganya no kubika, kandi wambare ibikoresho bikwiye byo kurinda nka laboratoire ya laboratoire no kurinda amaso.
