Nalpha-FMOC-L-Glutamine （CAS # 71989-20-3)

Intangiriro

Fmoc-Gln-OH (Fmoc-Gln-OH) ni aside amine ikomoka kumitungo ikurikira:

Kamere:

-Imiti ya chimique: C25H22N2O6

-Uburemere bwa molekulari: 446.46g / mol

-Ibigaragara: Umweru cyangwa hafi yera ya kirisiti cyangwa ifu

-Gukemuka: Fmoc-Gln-OH irashonga mumashanyarazi amwe n'amwe, nka dimethyl sulfoxide (DMSO) cyangwa N, N-dimethylformamide (DMF).

Koresha:

-Biochemiki yubushakashatsi: Fmoc-Gln-OH irashobora gukoreshwa nkitsinda ririnda mugice gikomeye cya synthesis ya peptide cyangwa proteyine.

-Iterambere ryibiyobyabwenge: Fmoc-Gln-OH irashobora gukoreshwa nkumuhuza muguhuza ibiyobyabwenge cyangwa peptide ikora mubuzima.

Uburyo bwo Gutegura:

Gutegura Fmoc-Gln-OH birashobora kugerwaho nintambwe zikurikira:

1. Ubwa mbere, glutamine ikoreshwa na fluoric anhydride (Fmoc-OSu) kugirango ibone fluoride ya Fmoc-Gln-OH (Fmoc-Gln-OF).

2. Hanyuma, Fmoc-Gln-OF isubizwa hamwe na pyridine (Py) cyangwa N, N-dimethylpyrrolidone (DMAP) mubihe byibanze kugirango bibyare Fmoc-Gln-OH.

Amakuru yumutekano:

-Fmoc-Gln-OH muri rusange ifite umutekano mugihe gisanzwe gikora, ariko biracyakenewe kubahiriza inzira z'umutekano wa laboratoire.

-Mwitondere kwirinda guhura nuruhu, amaso cyangwa ururenda, kandi wirinde guhumeka cyangwa kuribwa.

-Mu gihe cyo gukoresha, urashobora kwambara ibikoresho bikingira umuntu, nka gants ya laboratoire, ibirahure byumutekano hamwe n imyenda ya laboratoire.

-Mu gihe habaye impanuka cyangwa ikibazo, shakisha ubufasha mugihe kandi uzane amakuru arambuye kumiti kugirango uyikoreshe.