Papaverine Hydrochloride (CAS # 61-25-6)
Kode y'ingaruka | R22 - Byangiza niba byamizwe R34 - Bitera gutwikwa R11 - Biraka cyane |
Ibisobanuro byumutekano | S22 - Ntugahumeke umukungugu. S45 - Mugihe habaye impanuka cyangwa niba wumva utameze neza, shaka inama zubuvuzi ako kanya (erekana ikirango igihe cyose bishoboka.) S36 / 37/39 - Wambare imyenda ikingira, uturindantoki no kurinda amaso / mu maso. S26 - Mugihe uhuye namaso, kwoza ako kanya n'amazi menshi hanyuma ushakishe inama mubuvuzi. S16 - Irinde amasoko yo gutwikwa. |
Indangamuntu ya Loni | UN 1544 6.1 / PG 3 |
WGK Ubudage | 1 |
RTECS | NW8575000 |
FLUKA BRAND F CODES | 8 |
TSCA | Yego |
Kode ya HS | 29391900 |
Icyiciro cya Hazard | 6.1 |
Itsinda ryo gupakira | III |
Uburozi | LD50 mu mbeba, imbeba (mg / kg): 27.5, 20 iv; 150, 370 sc (Abalewi) |
Papaverine Hydrochloride (CAS # 61-25-6)
Papaverine hydrochloride, CAS nimero 61-25-6, ni uruganda rukomeye murwego rwa farumasi.
Urebye imiterere yimiti, nuburyo bwa hydrochloride ya papaverine, kandi imiterere yimiti igena imiterere yayo. Gutunganya atome no gutondekanya imiyoboro ya chimique mumiterere ya molekile itanga ituze ridasanzwe hamwe na reaction. Ibigaragara muri rusange byera kugeza byoroshye ifu yumuhondo ya kristalline, ifasha gutunganya, kubika no gutwara ibiyobyabwenge. Kubijyanye no gukemuka, ifite ubushobozi buke mu mazi, kandi ibidukikije bitandukanye bishingiye kuri aside hamwe nubushyuhe bwubushyuhe bizagira ingaruka kumiterere yabyo, ibyo bikaba bifite akamaro kanini mugushinga ibiyobyabwenge, guteza imbere dosiye, nuburyo bwo kwemeza kimwe gukwirakwiza ibiyobyabwenge mugihe utera inshinge no gutegura umunwa.
Kubijyanye na farumasi ikora neza, Papaverine Hydrochloride iri mubyiciro byoroheje imitsi yoroshye. Ikora cyane cyane kumitsi yoroshye yimiyoboro yamaraso, gastrointestinal tract, biliary tract nibindi bice, kandi iteza imbere imitsi yoroshye kuruhuka hakoreshejwe uburyo bwo gutwara calcium ion yo mu nda. Mubuvuzi, bukoreshwa kenshi mukuvura ischemia iterwa na vasospasm, nko kubabara umutwe no kuzunguruka biterwa na vasospasm yubwonko, bishobora guteza imbere umuvuduko wamaraso waho; Ifite kandi ingaruka zikomeye zo kugabanya ububabare bwo munda na coli biliary iterwa na spasima gastrointestinal, igabanya ububabare bw'abarwayi.
Ariko, kimwe nimiti myinshi, ni ngombwa gukurikiza amabwiriza ya muganga mugihe uyakoresha. Bitewe n'imikorere itandukanye hamwe n'indwara zishingiye ku barwayi ku giti cyabo, abaganga bakeneye gupima byimazeyo imyaka umurwayi afite, umwijima n'impyiko, indi miti ifatwa n'ibindi bintu, kandi bakagena neza igipimo, inzira y'ubuyobozi n'inzira y'imiti, bityo nko kwemeza ko imiti ifite umutekano kandi ikora neza, kandi igafasha umurwayi gukira. Hamwe niterambere ryubushakashatsi bwa siyanse, ubushakashatsi niterambere ryimiterere mishya ya dosiye no gutezimbere imiti ikomatanya nayo irashyuha.